In the analyses including potential prognostic factors of iCCA, high expression of FGF19, FGF21, and FGFR4 was associated with better OS (FGF19, adjusted HR = 0.38 [0.18–0.81], p = 0.012; FGF21, adjusted HR = 0.41 [0.19–0.89], p = 0.024; FGFR4, adjusted HR = 0.32 [0.14–0.72], p = 0.006). This evidence concerns the gene FGF21 and infantile convulsions and choreoathetosis.