Of note, the IL‐10‐secreting cells in this analysis contained both IFN‐γ+IL‐10+ and IFN‐γ−IL‐10+ cell populations and it was previously shown that the IFN‐γ+IL‐10+ T cell population in RA patients contributed mostly to disease 9. This evidence concerns the gene IFNA1 and rheumatoid arthritis.