Many reports later described additional mutations that broadened the phenotypic spectrum further, adding Emery–Dreifuss muscular dystrophy (EDMD) and hypertrophic cardiomyopathy (HCM) with no or minimal musculo-skeletal involvement to the clinical presentations of FHL1 mutations (Gueneau et al. 2009; Friedrich et al. 2012). The gene discussed is FHL1; the disease is hypertrophic cardiomyopathy.