There is no recommended amount for these substrates.Hyperglycemia should be managed by adjusting carbohydrate intake (it may benecessary to reduce intake to less than 100g/day), the use of specific formulasfor diabetes, and the administration of subcutaneous NPH insulin (andsubcutaneous simple insulin given as a fixed dose or as a rescue dose).Intravenous insulin use should be the exception and must be avoided as much aspossible. The gene discussed is INS; the disease is diabetes mellitus.