Oh et al. (16) examined nine SNP frequencies in the genes encoding TLR1, TLR2 (R753Q and A-16934T), TLR4, TLR9, and toll-IL-1 receptor domain-containing adaptor protein in a case/control cohort of 136 adult AD cases and 129 healthy individuals. The gene discussed is TLR1; the disease is Alzheimer disease.