The development of highly sensitive serological tests such as anti-tissue transglutaminase (tTG autoantibodies), anti-endomysial antibody (EMA) and anti-deamidated gliadin peptides (anti-DGP antibodies) have facilitated the diagnosis of coeliac disease, particularly in asymptomatic patients or in patients with vague clinical presentations (5,6). The gene discussed is TGM2; the disease is celiac disease.