In addition, a recent study suggests that there may be functional redundancy between PIM and PI3K in breast cancer, and because PI3K is a known regulator of glycolysis, PIM may then play a role in regulation of glycolysis in MYC-overexpressing TNBC (Hu et al., 2016; Le et al., 2016). The gene discussed is PIM1; the disease is breast carcinoma.