It is important to note that while MYC is certainly overexpressed in this model, which mimics the clinically observed increase in MYC expression in TNBC, it was also confirmed by unbiased clustering of mRNA expression analysis that the MTB-TOM model does resemble the Basal/TN subtype of breast cancer (Pfefferle et al., 2013). Here, MYC is linked to breast cancer.