In hepatocellular carcinoma (HCC), MYC is found to be frequently amplified and/or overexpressed, and is associated with poorly differentiated tumors and poor prognosis (Shachaf et al., 2004; Calvisi and Thorgeirsson, 2005; Kaposi-Novak et al., 2009; Lim et al., 2014; Anderton et al., 2017). The gene discussed is MYC; the disease is hepatocellular carcinoma.