Furthermore, recent studies suggested that autophagy is required for mitochondrial function, lipid metabolism, growth, and fate of KRASG12D-driven lung tumor (Guo and White, 2013), as well as autophagy suppresses progression of KRAS-induced lung tumors to oncocytomas and maintains lipid homeostasis (Guo et al., 2013). The gene discussed is KRAS; the disease is oncocytic adenoma.