We found PMQ can increase Glut-4 and Cebp/α expression in 3T3-L1 adipocytes and the epididymal fat of HFD mice, thereby augmenting glucose consumption in fat cells, a change that may reduce serum glucose and lipid levels and appears to be at least partially responsible for the anti-metabolic disorder effects of this chemical. Here, CEBPA is linked to Other metabolic disease.