YAP1 and neoplasm: Transcriptional coactivator YAP1 (Yes-associated protein 1) (Available online: http://www.uniprot.org/uniprot/P46937) can act both as a coactivator and a corepressor and is the downstream regulatory target in the Hippo signaling pathway responsible for organ size control and tumor suppression by restricting proliferation and promoting apoptosis [38,39].