Co-localization of IQGAP1, F-actin and β-tubulin proteins at the nuclear envelope has been reported by Johnson et al. in MCF-7 (breast cancer epithelial cells), HT29 (colon cancer epithelial cells) and NIH3T3 (non-tumor embryonic fibroblasts) cell lines [61]. Here, IQGAP1 is linked to malignant colon neoplasm.