TGFB1 and colorectal carcinoma: Several lines of evidence have also shown that miR-20a, another member of the miR-17 family, promotes cancer progression by facilitating CRC cell line migration and invasion and upregulating the expression of epithelial-mesenchymal transition (EMT) markers, neutralizes the growth-repressive properties of TGF-β, and further enhances the ability of TGF-β to drive cancer cell migration, invasion, and metastasis [55,65,66].