LIGHT can function as a mediator of herpes viral cell entry, hence its acronym Herpes Virus Entry Mediator (HVEM), and one may speculate a further mechanistic role for LIGHT in this context given the evolving roles of herpes virus in fibrotic lung disease exacerbations38, but it may be informative to compare circulating vs. tissue measurements. The gene discussed is TNFSF14; the disease is lung disorder.