Recent evidence links periodontal disease with coronary heart disease and CKD.27 Other studies indicated that CRP predicts arterial stiffness in CKD patients.28 In CKD patients, the development and progression of ventricle dysfunction occurred with inflammation and mineral metabolism disorders.29 Inflammation and oxidative stress have been linked to the pathogenesis of plaque formation and plaque rupture,30 both of which are associated with worse cardiovascular outcomes.31 The present study found no differences in traditional risk factors between patients with and without cardiac events. The gene discussed is CRP; the disease is chronic kidney disease.