NFE2L2 and neoplasm: KEAP1 is a repressor of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) transcription factor controlling antioxidant response element (ARE)-driven gene expression,17 whilst MIF is a pro-inflammatory cytokine, whose expression in cancer correlates with tumour aggressiveness and metastatic potential.18 Both proteins have been previously identified as sulforaphane targets;17,18 however, this is the first time their interaction with sulforaphane has been observed in a cellular environment at endogenous expression levels.