Yang G.F. et al. (2010) evaluated the role of ATO and the degree of expression of the Fas protein of human osteosarcoma cells (Saos-2 cell line); the author affirms that ATO reduces cell proliferation according to the dose and time and increased the expression of the Fas protein, although other mechanisms are interested in this process (Yang G.F. et al., 2010). The gene discussed is FAS; the disease is osteosarcoma.