Using RT-PCR and Western blot assays to detect IGF-1R mRNA and protein expression in 26 osteosarcoma and non-cancerous bone tissues, Wang et al. (2012) concluded that insulin-like growth factor-1 receptor (IGF-1R) is an independent prognostic marker for osteosarcoma patients and that an increased expression of this molecule is correlated with metastasis of osteosarcoma (Wang et al., 2012). This evidence concerns the gene IGF1R and osteosarcoma.