APOE and Hypertension: The influence of other variables previously related to mortality in this sample was considered in a fully-adjusted model, as per Marioni and colleagues.26 These were: Moray House Test IQ-type score at age 11, paternal social class (five-point scale), years of full-time education, APOE e4 carrier status, smoking status (never, ex-smoker, current smoker), and self-reported hypertension, diabetes and cardiovascular disease.