This model allowed to monitor the motility of IFN-DCs (migrating IFN-DCs) through the immune-chamber, connecting-channels, and tumor-chamber, in the presence of either non-competitive signals (no-competition) or biochemical stimuli (competition) and also to evaluate the overall recruitment of IFN-DCs into the 3D tumor space (infiltrated IFN-DCs) and their interactions with SW620 cells (Fig. 2d). Here, IFNA1 is linked to neoplasm.