In glutaric aciduria type 1 (GA1, OMIM#231670), a rare inherited metabolic disease, deficiency of glutaryl-CoA dehydrogenase results in accumulation of the putatively neurotoxic metabolites glutaric and 3-hydroxyglutaric acid (GA, 3-OH-GA) in body tissues, particularly within the brain. This evidence concerns the gene GCDH and glutaryl-CoA dehydrogenase deficiency.