This present cross-sectional study further substantiated those findings by demonstrating increases in serum hsCRP, sICAM-1, E-selectin, MDA, oxLDL and ISP concentrations among patients with FH, which reflect greater risk of developing premature CAD in these patients with a mean age of 45.1 ± 1.21 years. The gene discussed is SELE; the disease is familial hyperaldosteronism.