Familial hypercholesterolaemia (FH) is a genetic mutation of autosomal dominant inheritance which affect genes encoding for low-density lipoprotein receptor (LDL-R), proprotein convertase subtilisin/kexin type 9 (PCSK9) or apolipoprotein B (apoB) resulting in marked elevation of LDL cholesterol (LDL-c) concentrations [9]. The gene discussed is PCSK9; the disease is familial hyperaldosteronism.