In the GADA+ restricted set, there were no association signals surviving correction for multiple comparisons, and the only signal showing a significant difference between LADA and T2D was the depletion of the TCF7L2 T allele (Pdifference = 5.03 × 10–4; Additional file 1: Table S6), where the T allele showed modest, albeit non-significant excess when compared to controls (OR = 1.088). This evidence concerns the gene TCF7L2 and type 2 diabetes mellitus.