Therefore, the studies included in our article mainly depended on a consensus, which met any two of the following criteria: Age < 40 years, normal menstrual cycle, basal FSH ≤ 10 IU/L, basal E2 < 60 pg/ml, AFC > 5, previous IVF attempts < 3, no previous poor response/OHSS history, no polycystic ovary syndrome (PCOS) / severe endometriosis. This evidence concerns the gene BRD2 and ovarian hyperstimulation syndrome.