U2AF1 and acute myeloid leukemia: To identify common aberrantly spliced genes associated with U2AF1 mutations, we performed a comparison of our RNA-seq data on U2AF1S34F erythroid and granulomonocytic cells with RNA-seq data from other studies, including common myeloid progenitors (CMPs) from a U2AF1S34F-transgenic mouse (26) and AML patient samples with U2AF1 S34 mutations (23) (Figure 3, G and H, and Supplemental data files 5 and 6).