Consistent with our previous observations, loss of LPP was dispensable for mammary tumour growth (Supplementary Fig. 4a–d); however, mice bearing tumours harbouring an LPP-shRNA possessed significantly fewer lung metastases when compared with mice bearing a LucA-shRNA-expressing tumours (Supplementary Fig. 4e,f). The gene discussed is LPP; the disease is neoplasm.