ANPEP and neoplasm: The potential mechanism of the DOC/peptide NPs inhibiting tumor growth in mice is illustrated in the Figure1: 1) Targeting tumor‐enriched‐cadherin by HAV sequence; 2) Targeting tumor‐enriched‐integrin and ‐CD13 by NGRRGD sequence; 3) Transportation of NPs into tumor cells through endocytosis; 4) Inducing antitumor effects by apoptosis‐inducing peptide AVPIAQK and DOC.