For example, Bindarit was efficacious in mouse models of Chikungunya and Ross River virus infections, where it was shown to ameliorate infections and disease.19, 20 Furthermore, Bindarit was able to reduce arthritic inflammation without showing any detrimental effect on virus clearance in these animal models of alphavirus infection.21 Therefore, the activity of Bindarit activity was determined to reduce pulmonary and serum CCL2 levels in a mouse model of H7N9 disease. Here, CCL2 is linked to infection.