Monocytes and neutrophils also express the integrins CD11c/CD18 (p150/95) and CD11d/CD18 which are not expressed on CD8+ T-cells and can interact with multiple extracellular matrix proteins.46, 47 Alternatively, the tumour endothelium can also express galectin-3, a member of the lectin family that binds specifically to β-galactosides through its carbohydrate-recognition-binding domain. The gene discussed is ITGB2; the disease is neoplasm.