The HLA-A*02:01 allele is arguably the most common and widespread major histocompatibility complex (MHC) class I allele with up to 60% population coverage in certain regions.14 CD8+ T-cell responses toward the HLA-A2/WT1126-134 RMFPNAPYL epitope (herein called WT1A) have been identified in various HLA-A2+ cancer patients. Here, CD8A is linked to cancer.