In this study just like ours, stroke severity was not significantly associated with IGF-I serum levels and the authors concluded that better improvement after cerebral ischemic stroke is in association with the higher IGF-I serum levels.9 Bondanelli et al.18 studied 42 patients during rehabilitation after ischemic stroke to evaluate the relationship between serum levels of IGF-I with stroke severity and outcome. Here, IGF1 is linked to ischemic stroke.