STAT3 and Miyoshi myopathy: As shown in Figure 6B-C (left panels), DHA strongly suppressed both constitutive and tumor cell conditioned medium (TCCM)-induced activation of STAT3 in both PBMCs and DCs, indicating that DHA can inhibit STAT3 signaling in immune cells and has the potential to counteract STAT3 activation induced by MM cell-released factors.