In various cancers, including ovarian endometriosis and endometrioid carcinoma, non-small cell lung cancer and cervical cancer, DAPK1 is down-regulated and thereby contributes to reduced sensitivity to apoptotic signal and increased tumor cell survival and proliferation, causing cancer development and recurrence (Christoph et al., 2006[1]; Tian et al., 2015[11]; Kwon et al., 2016[4]). The gene discussed is DAPK1; the disease is neoplasm.