Recently, Yamaguchi et al. [24] further demonstrated that p75NTR-positive cells express higher stem cell-related genes (Nanog, p63 and Bmi-1) and EMT-related genes (N-cadherin and fibronectin), exhibite higher abilities of the colony formation in vitro and the tumor formation in vivo than that of CD44 or CD90-positive cells. The gene discussed is FN1; the disease is neoplasm.