Four articles (reporting a total of 6 case control studies) involving 1,065 cases and 836 controls and 2 articles (reporting a total of 3 case control studies) with 792 cases and 559 controls were included in our meta-analysis of the MMP-1 rs1799750 1G > 2G and MMP-2 rs243865 C > T polymorphisms and glaucoma risk. This evidence concerns the gene MMP2 and glaucoma.