In addition, the lead variant rs2472591 at SPRYD7/DLEU2 was in high LD (r2 = 0.85) with rs790943, a cis-eQTL associated with expression of the nearby gene, TRIM13, in blood dendritic cells in tuberculosis patients [26] (S9 Table), suggesting the associations at the SPRYD7/DLEU2 locus may be involved in the regulation of nearby gene expression at TRIM13. The gene discussed is SPRYD7; the disease is tuberculosis.