CD4 and neoplasm: Investigation into immune mediators of the observed increase in tumor fibrosis and cell death in Tamoxifen+ α-Lactalbumin, revealed a significant increase in CD3+ T cells, CD4+ and CD8+ infiltrates in tumors treated with α-Lactalbumin specific cell transfer compared to those treated with non-specific antigen (OVA) primed lymphocytes (Figure 7, Top three panels).