Besides interacting with TCF/LEF, β-catenin also binds to p300/CBP, TATA-box binding protein (TBP), Pontin52, Reptin52, Brg-1, MUC1-C, SOX10, p68/p72, FOXM1, yes-associated protein 1 (YAP1) and FBW1, which are all involved in tumor development or progression. The gene discussed is TBP; the disease is neoplasm.