They analyzed 204,993 SNPs in 61,851 cancer cases and 74,457 controls of European descent in their meta-analysis and identified seven novel loci, among them the hSNM1B/Apollo region: rs974404 was inversely associated with prostate and lung cancers and rs12144215 was inversely associated with colorectal, breast and prostate cancers [89]. The gene discussed is DCLRE1B; the disease is Familial prostate cancer.