PVT1 and neoplasm: Plasmacytoma variant translocation 1 (PVT1) is a lncRNA transcribed from the 8q24 chromsomal region which also harbors the c-Myc oncogene and is among the most frequently amplified chromosomal sites in human cancers, with almost 20% of tumours being found to exhibit increased copy number for both c-Myc and PVT1 [325].