MALAT1 and hereditary clear cell renal cell carcinoma: MALAT-1 was also demonstrated to induce EMT in squamous cell carcinoma of the tongue via the Wnt/β-catenin signalling pathway [94], while MALAT-1 knockdown in renal cell carcinoma decreased expression of β-catenin and transcription factor c-Myc, a downstream effector of Wnt/β-Catenin signalling [94].