MALAT-1 (metastasis associated lung adenocarcinoma transcript 1; also, called NEAT2 or nuclear enriched abundant transcript 2) was one of the first lncRNAs to be associated with tumourigenesis and was identified as a predictive marker for the development of metastatic disease and shorter survival in early stage lung adenocarcinoma—lung adenocarcinomas expressing high levels of MALAT-1 display almost 5 times the risk of metastasis as tumours with low expression [274]. This evidence concerns the gene MALAT1 and lung adenocarcinoma.