Because both a high mutational burden and chronic inflammation have been linked to PD1 receptor expression in patients with chronic inflammatory liver diseases 28 as well as in patients with other cancers, including non-small cell lung cancer (NSCLC),29 we were especially interested in PD1 expression patterns in patients with esophageal adenocarcinoma. This evidence concerns the gene PDCD1 and non-small cell lung carcinoma.