BOLA3 and Leigh syndrome: Mutations in all these genes except BOLA3 had been reported to cause LS (Tiranti et al. 1998; Budde et al. 2000; Fernandez-Moreira et al. 2007; McKenzie et al. 2011; Kopajtich et al. 2014; Peters et al. 2014; Gerards et al. 2013).