The analysis of CNVs in six regions corresponded to five genes previously associated with obesity, LEPR (intron 2 and intron 3), NEGR1, ARHGEF4, CPXCR1, and INS, and four intergenic regions (1p36.33b, 12q15c, 15q21.1a, and 22q11.21d). This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.