CD4 and tuberous sclerosis: Our results showed that transfer of CD4+ T cells primed against rmInα provided highly significant protection (P < 0.001) against the growth of I-10 TSC tumors (Fig. 3a) and that this protection provided a highly significant increase (P < 0.001) in overall survival compared to recipients of ovalbumin primed CD4+ T cells (Fig. 3b).