In previous experimental work using scn1a mutant larvae, which mimic well the epileptiform features of DS in ZF, we have shown that selective pharmacological agonists of the 5-HT1D, 5-HT2A and 5-HT2C receptor subtypes (GR 46611, TCB 2 and lorcaserin, respectively) substantially decreased the epileptiform activity. Here, PKM is linked to Dravet syndrome.