Moreover, we could demonstrate via gene expression profiling that the main transcriptional inducer of white adipocyte differentiation, PPARγ, was induced in epididymal adipose tissue in the murine peritonitis model whereas its expression levels were not changed significantly in the endocarditis model as well as in cultured adipocytes treated with TLR2-agonistic lipopeptides. The gene discussed is TLR2; the disease is endocarditis.