Those DEGs include genes important for: T-cell activation e.g. CD40 (FC = 348.51) and ZAP70 (Zeta-Chain (TCR) Associated Protein Kinase 70 kDa; FC = 140.3); chemotaxis e.g. CXCR5 (FC = 137.7) and CCR7 (FC = 94.1); cell cycle e.g. CCND2 (cyclin D2; FC = 55.7); apoptosis e.g. BCL2 (B-Cell CLL/Lymphoma 2; FC = 37.4); and lymphocyte development such as GATA3 (GATA Binding Protein 3; FC = 487.6) (Fig. 3h). This evidence concerns the gene CD40 and B-cell chronic lymphocytic leukemia.