ZNF146 and asthma: The zinc finger proteins cluster is linked to the core subnetwork in two ways: through direct interaction of CRMP1 protein, encoded by a nominally significant candidate, with IL33, known to be associated with asthma and part of the core network, and through functional relationship with IKZF3, a zinc finger transcription factor regulating B lymphocyte differentiation, encoded by a gene at the known 17q12-q21 asthma locus5, 6 and part of the core network.