VDR, RXR and PPARγ were detected in over 90% of triple negative BRCA1mut breast cancer and were significantly (VDR: p < 0.001, RXR: p = 0.010, PPARγ: p < 0.001) overexpressed in BRCA1 mutated as compared to sporadic cancer cases. This evidence concerns the gene BRCA1 and breast carcinoma.