This analysis revealed that the carriage of the FcγRIIA-131Arg/FcγRIIIA-176F/FcγRIIIBNA2 haplotype was associated with increased risk of severe malaria anemia relative to none carriage (OR = 1.70, 95% CI, 1.02–2.93, P = 0.036). Here, FCGR3A is linked to anemia.