GRM3 and bipolar disorder: Moreover, other candidate genes such as GRIA1, GRIA2, GABBR1, GABRG2, GABRR2, NRG2, NRG3, GRIK1, GRIK4, GRIN3A and GRM3, with functions that comprise formation of synapse, transmission of nerve impulse, behavior, learning or memory, are among families of genes that have been shown to have roles in neurological dysfunction jointly impacted in disorders like autism, schizophrenia and bipolar disorder [59–64].