Moreover, the expression of the collagen-related genes including PCOLCE2 (procollagen C-endopeptidase enhancer 2), COL9A3 (collagen type IX alpha 3), and COL22A1 (collagen type XXII alpha 1) were significantly changed in T2DM (Supplementary Table 2). This evidence concerns the gene COL9A3 and type 2 diabetes mellitus.