SMARCB1 and neoplasm: To delineate a signature for RT as compared with SD-NRT, we used two parallel methods, i.e., i) a Welch t-test comparing RT with all other SD-NRT (Supplementary Table 2), and then RT with each other individual SMARCB1-deficient tumor group (pair-wise analysis); a heat map of the 20 top genes for each group is depicted in Supplementary Figure 1; and ii) a NMF-based list, focused on the 20% most differential genes defined by the NMF method; this resulted in a short list of 161 genes, 50 overexpressed in RT and 111 overexpressed in SD-NRT (Supplementary Table 3).